If there is no systemic discomfort after squeezing out the pus from the granuloma, local medication or surgical treatment can be carried out under the guidance of the doctor. If there is systemic discomfort, oral or intravenous medication should be administered as soon as possible after the condition is clarified by the doctor. You should not squeeze the granuloma because squeezing the affected area increases the risk of intracranial infection and other complications. If the pus is squeezed out but not accompanied by systemic discomfort, you can choose topical medication, such as ofloxacin ophthalmic ointment, etc. If the pus is too large to be discharged on its own, a surgical incision is needed to drain the pus if necessary. When granuloma extrusion pus appeared fever, dizziness, headache and other systemic manifestations, may be granuloma caused by intracranial infection, the need for timely medical examination, and oral or intravenous input of antibiotics such as penicillin, intracranial infection control, serious cases may be life-threatening patients need emergency rescue. When suffering from granuloma, it is recommended to consult a doctor for examination and treatment, do not squeeze or medication on your own, so as not to lead to adverse consequences.