Subacute thyroiditis can be treated with prednisone when the condition is severe, prednisone has an anti-inflammatory, immunosuppressive effect, this disease can also be used aspirin, propranolol and other drugs, need to comply with the doctor’s instructions to use drugs. Subacute thyroiditis is an acute inflammatory lesion of the thyroid gland, and prednisone is a glucocorticoid drug that can play an anti-inflammatory and immunosuppressive role, so prednisone can be used to treat subacute thyroiditis, and can effectively reduce clinical symptoms. It should be noted that the majority of patients with subacute thyroiditis can be self-healing, acute pain is generally applied to aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs, such as glucocorticosteroids when the effect of drug therapy is not good. If the patient has thyrotoxicosis, also need to follow the doctor’s instructions to apply propranolol, atenolol and other beta-blockers. Subacute thyroiditis patients need to strictly comply with the doctor’s prescription medication, do not self-medication.