Symptoms of bleeding may occur when fibrinogen is less than 1g. Fibrinogen is a large molecule of globulin synthesized by the liver, which plays an important role in the body’s blood clotting process. The normal clinical range of fibrinogen is 2~4g/L. Decreased fibrinogen is mainly seen in the following types of diseases: 1. Cirrhosis of the liver or severe hepatitis will cause a decrease in its synthesis. 2. Diffuse hemolytic disease or fulminant purpura will cause its consumption to increase. 3. Primary hyperfibrinolysis causes an increase in its fibrinolytic function. Fibrinogen in its normal range usually does not show any symptoms, but when it is less than 1g / L, there may be bleeding phenomenon, this time to consult a doctor in a timely manner, under the guidance of the doctor for treatment.