The need for anti-inflammatory drugs in patients with pulmonary nodules is judged mainly by the size and nature of the nodule. Pulmonary nodules below 5mm are mostly benign inflammatory nodules with no clinical manifestations and do not require special treatment. If the blood count is high, it is necessary to consider whether the inflammation is related to the nodule. If it is related to nodules, diagnostic anti-infective treatment can be given, such as oral amoxicillin clavulanate potassium, cefuroxime, cefprozil, ofloxacin, moxifloxacin, azithromycin, etc. These antibiotics can be reviewed after 2 weeks of treatment. If the CT suggests that the nodule disappears, it indicates that the treatment of inflammatory nodules is effective. If the nodule is a malignant nodule with pleural pulling sign, pleural depression sign, short burr, lobulated and other changes, anti-inflammatory drug treatment is not needed, only dynamic chest enhancement CT examination and percutaneous lung puncture cytohistological examination if necessary are needed to understand whether early lung cancer occurs. If early stage lung cancer occurs, early surgery by a thoracic surgeon is required and anti-inflammatory drug treatment is not necessary.