In recent years, the incidence of non-gonorrhea has been rising, and in western countries, the incidence of non-gonorrhea ranks first among STDs. Since there is no effective medicine for non-gonorrhea, I often encounter many patients suffering from non-gonorrhea in my clinical work, spending thousands of dollars or even tens of thousands of dollars, running around in major hospitals, but the results are not satisfactory. Is it true that non-gonorrhea cannot be cured? In fact, the cause of non-gonorrhea has been clarified, and the treatment drugs are far more varied than those for gonorrhea, so it should be said that non-gonorrhea can be cured. The author analyzes the causes mainly as follows. The cause is complex, the symptoms are insidious, and the condition is often neglected by patients. Non-gonorrhea is a kind of urethritis caused by sexual contact. It seems that non-gonorrhea is not an independent disease, but rather a complete garbage can, and as long as the UTIs are not caused by gonococci, they are all thrown into this garbage can. The “main culprits” of non-gonorrhea are Chlamydia trachomatis and Mycoplasma hyopneumoniae. Data show that 40%-50% of non-gonorrhea is caused by Chlamydia trachomatis, 20%-30% is caused by Mycoplasma solium, and the rest of the “accomplices” are pathogenic microorganisms such as Trichomonas vaginalis, Herpes simplex and Candida albicans. Trichomonas vaginalis can cause up to 15% of cases of non-gonorrhea. The etiology of non-gonorrhea is really complex, as it causes not only urethritis but also cervicitis in women, so some scholars also call it “non-specific reproductive tract infection”. The incubation period of non-gonorrhea is longer than that of gonorrhea (2-10 days for gonorrhea and 7-21 days for non-gonorrhea). The main symptoms for women are increased leucorrhea, flushing of the cervix, edema, congestion, erosion, with mucous purulent discharge, and the symptoms of urethritis are often not obvious. However, most patients have hidden symptoms and mild performance, so they are often neglected. Unlike gonorrhea, after the onset of gonorrhea, the urethra keeps flowing out yellow sticky purulent secretions like semen, wetting most of the crotch, and the symptoms can be described as “drenching”. Even if they go to the hospital, they do not believe in the doctor’s words and refuse to be examined and treated. According to some data, the consultation rate of gonorrhea within 4 days of its onset is 80%, while that of non-gonorrhea is only 30%-40%. If non-gonorrhea is not treated in time, it can be combined with epididymitis, prostatitis, urethral stricture and infertility in men; acute tubal infection, endometritis, ectopic pregnancy and infertility in women. The treatment at this point is more difficult. Therefore, any patient with a history of non-marital sexual contact should go to the hospital in time for a comprehensive examination, early diagnosis and early treatment, with a view to achieving early healing. You can’t avoid treatment because you don’t feel it, so it won’t become a big problem. Don’t forget to bring your sexual partner with you when you go to the hospital, if you only treat one side, otherwise, even if your STD is cured, it will cause mutual transmission between sexual partners playing ping pong. It is worth noting that most gonorrhea patients are often combined with chlamydial infection, and since the rate of underdiagnosis is quite high in many areas of China with the application of chlamydial antigen testing, drugs for chlamydia should be routinely applied while treating gonorrhea. The fact that many patients have to drink alcohol or even stay up all night due to their work and socializing, which leads to excessive physical and mental overdraft, often causes the immunity of the body to decline, leading to the resurgence of pathogens, which rampage in the body and multiply. Some patients, once their condition has slightly improved, immediately throw the doctor’s instructions to the wind, smoking and drinking, indulging in nightlife, frequenting pornographic places, leading to re-infection with STDs, the result of which is that one disease is not healed, and other diseases rise again, eventually leading to a variety of STDs, mixed infection, increasing the difficulty of treatment of non-gonorrhea, bringing great trouble to the treatment. Therefore, it is important to abide by sexual morality, be clean, use condoms, follow medical advice, combine work and rest, and regulate diet to prevent and treat STDs. Failure to correctly select sensitive antibiotics The cause of non-gonococcal urethritis is well understood, but there is no antibiotic that can completely cure STDs caused by the same pathogen in different individuals. In other words, there are no specific drugs for treating non-gonorrhea. The main drugs that are usually used to treat non-gonorrhea clinically are tetracyclines (tetracycline, doxycycline, memantin), macrolides (erythromycin, azithromycin, cross-famil, clarithromycin, roxithromycin), quinolones (gatifloxacin, levofloxacin, sparfloxacin, lomefloxacin, pefloxacin). Among these drugs, some patients use azithromycin to treat non-gonorrhea with special effects, while for some patients there is no effect, this is because these patients are infected with strains resistant to the drug, which shows that the interaction between drugs and bacteria is an extremely complex process, at present, the drug sensitivity test in many areas of China shows that the rate of quinolone resistance is relatively high, and the trend is increasing year by year. Therefore, clinical selection of quinolones for the treatment of non-gonorrhea should be cautious, unless the drug sensitivity test shows that the drug is a sensitive drug. For departments that have the conditions to carry out laboratory tests for sexually transmitted diseases should try to select therapeutic drugs according to the drug sensitivity test. In the process of medication, the dose is sufficient, the course of treatment should be sufficient, and we should be alert to the adverse effects of drugs (especially tetracyclines and quinolones), pregnant women can only choose erythromycin treatment, for some patients after repeated treatment, mycoplasma is still recurrent, we should consider the following reasons: ① not according to the drug sensitivity selection of sensitive antibiotics, should be treated with sensitive drugs; ② data show that about 20-30% of normal people Therefore, we should correct the misconception that mycoplasma infection in the genital tract is an STD or a disease, if the patient does have a history of unclean intercourse, the symptoms all disappear after repeated treatment according to drug sensitivity, but repeated tests are still positive for mycoplasma, treatment should be abandoned, endless application of antibiotics is bound to cause damage to the body’s liver, kidneys, blood and other systems and secondary infection The long-term treatment will also bring great mental and economic pressure to the patient, not to mention that in this case mycoplasma is no longer harmful to the organism.