Multiple gallbladder stones need to be treated with medication, surgery, gastrointestinal decompression and other treatments according to the condition, medication mainly relieves the symptoms, surgery is a more effective method. 1. Medication. Need to choose the appropriate drugs according to the condition, all drugs need to be used under the guidance of a doctor, if there is an adverse reaction to the use of timely consultation. (1) stone dissolving drugs. Such as ursodeoxycholic acid, goose deoxycholic acid, etc., mainly for cholesterol stones in the gallbladder, but the effect of treatment is still unclear. (2) Antispasmodics. Such as scopolamine, atropine, etc., targeting abdominal colic caused by spasm of the gallbladder and bile ducts, can relieve pain. (3) Analgesics. Drugs such as ibuprofen can relieve abdominal pain. (4) Antibiotics. Such as clindamycin, ampicillin, cephalosporin, levofloxacin and other drugs, mainly for bacterial infection, can kill pathogens and reduce inflammation. 2. Surgical treatment. It is necessary to judge whether it is suitable for surgical treatment according to the condition, but the effect of surgical treatment is clearer, that is, cholecystectomy through surgery, including laparoscopic surgery and open surgery. 3. Gastrointestinal decompression. For people with serious clinical symptoms, gastrointestinal decompression can be chosen to reduce the pressure on the stomach and gallbladder. It is recommended that the people concerned should consult the doctor in time for a clear diagnosis, and then appropriate treatment should be carried out according to their conditions.