Bitter mouth with cold and fever is often caused by inflammation of the mucous membrane of the upper respiratory tract due to the invasion of pathogens in the body, which causes fluctuations in body temperature to rise and abnormalities in the taste buds in the mouth, resulting in bitter mouth. At this time, physical cooling and antipyretic agents can be given to lower the body temperature, and a little icing sugar can be taken to improve the symptoms of bitter mouth, and icing sugar also has the effect of clearing the lungs, resolving phlegm and relieving cough. The pathogen of cold can be identified by blood test, and the result of the test can be used to identify the cause of the disease and treat the cause.