What to do if you have high transaminases on atorvastatin

Taking Atorvastatin for high aminotransferases requires different measures depending on the degree of elevated aminotransferases. The primary role of atorvastatin is in the treatment of hypercholesterolemia, mixed hyperlipidemia, and in the management of coronary heart disease and stroke. Reversible elevations of serum aminotransferases can occur occasionally while taking atorvastatin. Different levels of transaminase elevation have different management measures: 1. When the level of aminotransferase is higher than three times the normal value, statins should be immediately discontinued, replaced by niacin for lipid-lowering therapy, and liver-protecting drugs should be taken until the level of aminotransferase returns to normal. 2. When the transaminase level is between 1.5 and 3 times the normal value, the dosage of statins should be reduced by half, and liver-protecting drugs should be added, and liver function tests should be performed once every two weeks. 3. When the level of aminotransferases is within 1.5 times the normal value, statins can continue to be used according to the original dosage, but liver function should be tested once every two weeks. Therefore, there exist different countermeasures for high transaminases induced by taking atorvastatin, but the specific treatment needs to be evaluated by a professional doctor according to the specific condition.