The harm of taking Wu Ji San for a long period of time is not clear, but it may cause the body to develop drug resistance. Wu Zhi San is composed of Cang Zhu, Platycodonopsis, Citrus aurantium, Pericarpium Citri Reticulatae, Paeoniae Alba, Angelica Dahurica, Rhizoma Ligustici Chuanxiong, Radix Angelicae Sinensis, Glycyrrhiza Uralensis, Cinnamon, Poria, and Semen Xie, which has the effects of dispersing cold and removing dampness, regulating qi and activating blood circulation, and resolving phlegm and eliminating accumulation. It is used for treating external wind-cold, internal cold, chest and abdominal congestion, vomiting and malnutrition, head and body pain, shoulder and back constriction (spasms and convulsions due to wind-cold), as well as women’s blood-qi imbalance, heart and abdominal pain, etc. Not only Wuji San, but also most of the other herbs, are also used in the treatment of cold and dampness. Not only is Wuji San, most prescriptions or drugs used for a long time may make the body develop drug resistance, and, Wuji San belongs to the traditional Chinese medicine prescription, Chinese medicine emphasizes the identification of evidence-based treatment, the process of taking traditional Chinese medicine, it is necessary to consult the doctor at regular intervals, the doctor will adjust the prescription according to the patient’s latest physical condition, the ratios of the traditional Chinese medicine prescription is not set in stone. Patients are advised to use the medication under the guidance of a doctor.