Vitamin A cream can cure spots on the skin. Spots are caused by pigmentation, and the causes are mainly chloasma, freckles, nevus of Ota, etc. Various reasons lead to melanin deposition, which affects the skin’s beauty. The main ingredient of retinoic acid cream is retinoic acid, which can affect the melanin production of melanocytes and reduce the skin pigmentation, so as to improve the pigmentation on the skin. Improper use of retinoic acid cream may cause skin irritation, such as burning sensation, erythema and flaking, which in most cases can be adapted and tolerated, and the irritation may gradually disappear. If irritation persists or worsens, intermittent use or discontinuation of the product is recommended. It is contraindicated in women during the first 3 months of pregnancy and in patients with acute or subacute dermatitis or eczema. Although Vitamin A cream can lighten the skin spots, but for the more serious spots simply using Vitamin A cream, the therapeutic effect is not good, often can not be cleared, but also need to be combined with other treatments, such as laser therapy, systemic medication therapy and so on. For patients with spots on the face, they should go to the dermatology department of a regular hospital, after clarifying the cause of the disease, under the guidance of the doctor, avoid self-medication.