You can’t just rely on the abnormal elevation of CA199 value to confirm the diagnosis of pancreatic cancer. CA199 is a common tumor marker in the clinic, often used as an important indicator for diagnosing malignant tumors, and has a certain suggestive role in the diagnosis of malignant tumors, but cannot be used as the basis for a single confirmation of the diagnosis. Many benign diseases can also cause elevated CA199, such as hepatitis, pancreatitis, cholecystitis, biliary obstruction, intestinal obstruction, etc. It is mainly because when inflammation and obstruction occurs, the fluid in the lumen is not discharged well, the permeability of blood vessels is increased, and the rate of lumen contents entering the blood vessels is increased, which leads to the elevation of CA199 in blood circulation. In addition to pancreatic cancer, some malignant tumors also cause CA199 elevation, such as gastric cancer, gallbladder cancer, liver cancer, colon cancer and so on. Commonly used tumor markers for pancreatic cancer include CA199, CEA, CA50, etc., with different positive rates. Serum CA199 is the most commonly used diagnostic marker for pancreatic cancer, and its sensitivity for diagnosing pancreatic cancer is 79%~81% and specificity is 82%~90%. The diagnosis of pancreatic cancer should be based on symptoms, signs, imaging manifestations, pathological manifestations, immunology and other indicators for comprehensive diagnosis, and a single indicator can not be used as the basis for confirming the diagnosis. If you find discomfort, you should go to the hospital in time and be diagnosed under the guidance of professional doctors.