The difference between non-invasive DNA and Down’s pregnancy test is the accuracy rate, which is higher for non-invasive DNA. Down’s refers to Down’s syndrome screening, which generally involves extracting the serum of a pregnant woman, testing the serum for alpha-fetoprotein, human chorionic gonadotropin, free estriol, and other indicators, and then combining them with the pregnant woman’s gestational week, weight, and other comprehensive analyses to calculate how high the chances of the fetus having a Down’s syndrome child are. Non-invasive DNA is generally through the peripheral blood of the pregnant woman, extracting the free DNA of the fetus, using sequencing technology, comprehensive biological analysis, can accurately conclude the risk of chromosomal abnormalities in the fetus. Non-invasive DNA is usually relatively convenient and safe with a high degree of accuracy, although it can be chosen based on the pregnant woman’s own situation.