Causes of cauliflower-like granulation on toes include onychomycosis, athlete’s foot, plantar warts, corns, and so on. 1. Inflammation of the nail: in the case of onychomycosis, the bacterial infection is triggered by the irritation of the nails, which leads to a granulomatous reaction around the nails and the phenomenon of cauliflower-like granulation on the toes. 2. Tinea pedis: In the case of tinea pedis, due to fungal infections, these fungal stimulation of the toes can lead to hyperplasia of the skin of the toes, resulting in the appearance of granulomatous material. 3. Plantar warts: In the case of plantar warts, wart-like growths can appear on the toes due to human papilloma virus infection. 4. corns: when the toe is worn for a long time, it triggers the proliferation of keratin, and also the appearance of cauliflower-like granules. Finally, the phenomenon of growing cauliflower-like buds on the toes, please go to the hospital in time to check, clarify the cause of the disease, symptomatic treatment.