What is the cardiac enzyme profile?

Myocardial enzyme profile is a general term for a series of enzymes in the body. Since myocardial enzymes are often released during myocardial necrosis, the extent of myocardial cell damage can be measured by the level of myocardial enzymes in the blood. The cardiac enzyme profile mainly includes creatine kinase, creatine kinase isoenzyme, lactate dehydrogenase, glutamate transaminase, and glutamic oxalacetic transaminase, all of which may be elevated in different diseases. Especially when there is acute myocardial infarction, myocarditis, acute phase of stroke and acute cerebrovascular disease, elevation is more common.1. Acute myocardial infarction: After acute myocardial infarction occurs in patients, the specific creatine kinase isoenzyme in the myocardial enzyme profile usually starts to rise 4-6 hours after acute infarction, will peak around 24 hours and return to normal in 48-72h. Doctors can combine such dynamic evolution and diagnose whether a patient has acute myocardial infarction based on the patient’s symptoms and ECG changes; 2. Myocarditis: after the occurrence of myocarditis, elevated myocardial enzyme profiles will also be found, but patients with myocarditis will have longer enzymatic changes than infarction. At the same time, patients may have different manifestations such as chest tightness, palpitations, arrhythmias and heart failure; 3, acute stage of stroke and acute cerebrovascular disease: If the patient is in the acute stage of stroke, or acute cerebrovascular disease occurs, more enzymes are released due to brain tissue damage and sympathetic excitation increases catecholamine secretion, resulting in patients with secondary myocardial injury, which in turn increases the value of cardiac enzymes in the serum; 4, other 4, Other: Some muscle strains, fractures, rhabdomyolysis, hypothyroidism, nephritis, pneumonia, malignant tumors, leukemia, hepatitis, extrusion syndrome, etc. can also cause destruction of cardiomyocytes and other tissue cells, which can lead to elevated cardiac enzymes. When a patient has symptoms of elevated cardiac enzymes, the diagnosis should be confirmed by combining other specialized laboratory tests and clinical symptoms, followed by targeted treatment.