Thickening of the pleura of the apical pleura of both lungs is the result of chest imaging, which may be caused by pleurisy, or by tuberculosis, or by lung cancer. 1. Pleurisy: pleurisy is an inflammation that occurs in the pleural cavity, the disease can lead to thickening of the pleura of the apical pleura of both lungs of the patient, and the patient can also have symptoms such as chest tightness, shortness of breath, dyspnea, etc. The treatment can be given to penicillin, cephalosporin, fluoroquinolone and other drugs for treatment, and streptokinase and other medications to reduce the thoracic cavity adhesion medication can also be used. 2. Tuberculosis: tuberculosis is a kind of disease caused by Mycobacterium tuberculosis infection, which can lead to thickening of the pleura of both lungs and symptoms such as cough, sputum and blood in sputum, etc. Isoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin, etc. can be used for treatment. 3. Lung cancer: lung cancer is a kind of malignant tumor originated from bronchial mucosa or glands in the lungs. Lung cancer can also lead to thickening of apical pleura of both lungs, and the patients can also have symptoms such as blood in sputum, irritating dry cough, chest pain, etc. Treatment can be carried out through surgery, chemotherapy, targeted therapy, radiotherapy, etc. If the examination finds that there is blood in sputum, the patients can use drugs such as isoniazid, pyrazinamide, ethambutol, streptomycin, etc. to treat the disease. If examination reveals thickening of the pleura of both lung apices, it is recommended to consult a physician to identify the cause and dispose of it.