Whether endometrial thickening is serious should be judged according to the causes leading to thickening, the specific analysis is as follows: 1. Not serious: normally the endometrium is thinner just after menstruation, with the growth of estrogen, usually thicker before menstruation, the endometrium is shed when menstruation comes, the endometrium becomes thinner after shedding, which is a physiological phenomenon, do not worry. Some endometrial thickening is pathological but not serious, such as irregular menstruation, endometrium growing under the action of estrogen, not ovulating or insufficient luteinizing function after ovulation, resulting in insufficient progesterone in human body, thus endometrial thickening causes abnormal bleeding, but it is a benign lesion, which needs to be detected and treated in time for better treatment effect. Sometimes progesterone deficiency leads to long-term stimulation of endometrial polyps, resulting in local thickening, most of which are benign lesions and can be removed surgically, and smaller polyps can also be treated by medication, which is usually not serious; 2. Serious: If endometrial thickening is a malignant lesion, such as endometrial cancer, it can be manifested as thicker endometrium, usually accompanied by vaginal bleeding. Usually endometrial thickening caused by malignant tumors of the endometrium is more serious, and if it can be detected and treated early, the treatment effect is usually better.