Symptoms of leg weakness in patients with cerebral infarction can be treated by administering nutritive neurologic medications, medications to improve circulation, antiplatelet agents, and symptomatic support. Cerebral infarction can occur with motor, sensory, emotional, consciousness, autonomic dysfunction and other manifestations, which may leave symptoms or sequelae of limb weakness. Generally speaking, patients with cerebral infarction can take piracetam, vitamin B12 and other nutritive nerves; take caproxetine and betahistine to improve circulation; take aspirin, clopidogrel and other antiplatelet aggregation; as well as lowering blood pressure medications, such as valsartan, and lowering glucose medications, such as glimepiride, etc., for treatment. Cerebral infarction patients with leg weakness should also undergo rehabilitation training, should be standardized medication and exercise under the guidance of professional physicians. It is recommended that patients seek timely medical treatment.