Increased urine protein is mostly caused by glomerulonephritis. Its treatment includes the following aspects: First, if the 24-hour urine protein quantification is less than 1g, angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists can be applied. These two drugs can lower urine protein while lowering blood pressure. Second, patients who reach nephrotic syndrome, it is best to perform renal puncture biopsy and apply immunosuppressive therapy according to the type of pathology. Commonly used immunosuppressants, including glucocorticoids, tacrolimus, cyclosporine, raglan polysaccharide, morte-macrolimus, azathioprine, monoclonal antibodies, etc. Third, treatment of complications, including lipid-lowering therapy, anticoagulation, anti-platelet aggregation, diuretic and anti-swelling, and antihypertensive, etc.