There are many drugs for regulating menstrual cycle, but there are also many causes of menstrual irregularities, and the causes must be identified before applying drugs for regulating menstrual cycle. Commonly used estrogens include Glivec and Bemelia; progestins include progesterone, dydrogesterone, norethindrone, and methylhydroxyprogesterone. The combination of estrogen and progestin includes Fentanyl, Clomid, and short-acting oral contraceptive pills. It is important to identify the specific cause of menstrual irregularities according to the patient’s specific situation before administering the medication. It is important to pay attention to diet regulation. Obese patients or patients who are thin can also cause irregular periods, and in this case, if they lose weight or gain weight, their periods can return to normal.