Increased maternal D-dimer is mainly a physiological elevation, mainly due to pregnancy, the blood system will be stimulated by pregnancy physiological changes, such as elevated white blood cells, lower hemoglobin, and the emergence of hypercoagulation, hypercoagulation will appear D-dimer elevation, D-dimer elevation should be less than four times the upper limit of the reference range. If the increase in D-dimer is very severe, exceeding five times the upper limit of the normal range, it should be taken seriously and should be combined with other coagulation indicators to determine whether there is a prone to embolism. If thrombophilia is present, anticoagulation therapy with aspirin or low molecular heparin calcium is indicated. If the D-dimer increases after delivery, it is easy to produce thrombosis, so it is important to get out of bed promptly after delivery to avoid thrombosis caused by sitting or lying down for a long time.