If the patient has a sore throat and the medication is not effective, it means that the inflammation of the patient’s throat is more serious. It is recommended that the patient change the oral medication to antibiotic drip, clinically commonly used is cefazolin injection, cefuroxime sodium injection, ceftriaxone injection or cefoperazone injection, the patient can selectively apply, or under the guidance of the doctor, before using the medication are required to do skin test. At the same time, patients can also be combined with Andrographis injection, or phlegm fever clear injection together to anti-inflammatory and reduce swelling, and can also be combined with budesonide suspension for nebulized inhalation treatment. After active treatment, the patient’s condition should improve significantly. If it still does not improve, it is best to go to the ENT department of the hospital for a detailed examination to clarify the patient’s specific situation so as not to delay the patient’s condition. During this period, patients must not smoke, drink alcohol and stay up late.