Taking watermelon cream for sore throat should be effective if the painful symptoms are not particularly obvious, but if the symptoms are more pronounced, it is recommended to use anti-inflammatory drugs and anti-viral drugs. Because most inflammation in the throat is caused by positive cocci and viral infections, oral penicillin or cephalosporins are more effective. Anti-viral drugs can be better with diflucan or busulfan. If the symptoms are more pronounced, even with restricted mouth opening or difficulty swallowing, or even difficulty breathing, it is still recommended to go to the hospital to check for peri-tonsillitis or acute epiglottitis. If these two conditions are present, hormonal treatment is needed to get better faster, but if it is epiglottitis, hospitalization is recommended because epiglottitis can cause respiratory distress and even life-threatening. Therefore, if the pain is obvious it is advisable to use the medication with caution.