The skull is a group of hard bones, which plays a great role in human health. It builds a strong fortress for the brain so that the intracranial tissues can operate and work normally. If the skull is damaged, the intracranial environment and intracranial pressure will become very unstable, which will cause a series of cranial defect syndrome and seriously affect the life and health of patients. Cranial defects should be taken seriously, and if the defect area is larger than 3cm, it is necessary to go to the hospital for cranial repair surgery in time. In neurosurgery, skull repair surgery is a very classic surgery, which has thousands of years of history and mature technology, so many hospitals can do it, but the focus is on the recovery and effect after surgery. The most important factor that really affects the outcome of the surgery is the repair material. Currently most local hospitals use titanium mesh material, which is a metal material and not expensive, but post-operative problems occur, so it is better to choose a safer and advanced material for skull repair surgery. Currently, we use a highly engineered plastic called PEEK, which is an advanced polymer material that is particularly close to autologous cranial bone in all of its properties. In addition to the material, the physician’s experience and approach are also very important. We not only use advanced PEEK repair material, but our team continues to improve and upgrade the technology, and also incorporates the concept of cosmetic surgery into the surgery, making the post-operative results more natural-looking and satisfying for patients and families.