The treatment of multiple hypoechoic nodules in the thyroid gland depends mainly on the nature of the nodules. If the nodule is benign, targeted treatment can be taken according to the primary disease; if it is malignant nodule or benign nodule produces pressure and other symptoms, surgical treatment can be performed. 1. Benign nodules: For benign multiple hypoechoic thyroid nodules with normal thyroid function and no obvious clinical symptoms, regular review is sufficient. For patients with abnormal thyroid function, targeted treatment can be taken, such as patients with hypothyroidism can take levothyroxine sodium tablets, and patients with hyperthyroidism can take antithyroid drugs, such as methimazole, propylthiouracil and so on. 2. Other: for malignant nodules or benign nodules produce pressure and other symptoms, surgical treatment can be taken. Patients with multiple hypoechoic nodules in the thyroid gland are advised to go to the hospital and ask the doctor to make a judgment and give a treatment plan.