Hypertrophic cardiomyopathy is a hereditary cardiomyopathy whose diagnosis is based on the patient’s past medical history and associated symptoms and signs, combined with ancillary tests echocardiography suggesting a diastolic septal thickness of 15 mm, and asymmetric hypertrophy of the ventricles can be seen without significant enlargement of the ventricular chambers. Cardiac magnetic resonance suggests limited or generalized thickening of the ventricular wall, and characteristic changes such as myocardial lamellar enhancement can be seen on isotope delayed enhancement scans. A positive family history is more helpful in making a definitive diagnosis. In patients with hypertrophic cardiomyopathy, further genetic testing may be performed to identify genetic abnormalities. Hypertrophic cardiomyopathy is one of the leading causes of sudden death in adolescents and sports and requires an aggressive and definitive diagnosis in order to take measures to prevent sudden death.