Chondromalacia patella is an osteoarthropathy in which the articular cartilage in the patellar region degenerates. Generally, it is not curable, but the clinical symptoms can be relieved or disappeared through conservative treatment or surgical treatment. Chondromalacia patella mainly manifests as softening and wearing of the patellar cartilage, and the clinical symptoms are pain and discomfort in the knee joint and impaired joint movement. Mild chondromalacia patella can be treated conservatively, such as rest, quadriceps exercise, etc., oral non-steroidal drugs such as aspirin, nimesulide, etc. to relieve pain, choose glucosamine and other drugs to nourish the cartilage, as well as physical therapy, acupuncture, massage and other physical therapy. If chondromalacia patella is more serious such as dislocation or semi-dislocation of the patella, it is recommended to choose surgical treatment, such as ligament release or transfer surgery. In addition, we should pay attention to keep warm in daily life and reduce the movement of the knee joint such as going up and down the stairs, climbing mountains, etc., so as not to aggravate the symptoms. The above medications should be taken under the guidance of a medical professional.