The hazards of unpaid blood donation are mainly fainting, anemia, etc. The benefits are that it can rescue patients and promote one’s own hematopoiesis. 1. The hazards of unpaid blood donation are mainly fainting, paleness, etc. due to the loss of part of the blood volume in a short period of time, resulting in a reduction of blood volume, and some people may also suffer from anemia. Informal organizations collecting blood and reusing blood collectors may lead to infection of hepatitis B and other infectious diseases. 2. The benefits of gratuitous blood donation are mainly that blood can rescue patients in need of blood and even save lives; it can promote bone marrow hematopoiesis in one’s own organism and accelerate blood cell turnover. In addition, blood type and some biochemical tests can be conducted free of charge before blood donation. Through the pre-donation examination, the occurrence of fainting and other adverse reactions after blood donation can be significantly reduced, and blood donation is beneficial to oneself and others, so healthy people can donate blood on a regular basis. The process of blood donation should be carried out under the guidance of a physician.