The vast majority of people who take medication are concerned about the use and dosage of drugs, but do not know that the temperature of the water for medication is also very delicate. The medication should not be taken with hot water (generally refers to 60 ℃ and above), because some medicines will be physically or chemically reactive when exposed to heat, thus affecting the efficacy of the treatment. Here we take a look at which drugs should not be served with hot water. 1, high temperature will be inactivated drugs, including digestive enzymes, a variety of live vaccines and preparations containing active bacteria. Enzymes are active proteins that are denatured and solidified by heat, leading to a decrease in efficacy or disappearance. Commonly used are pepsin combination, compound amylase oral solution, pancreatic enzymes, multi-enzyme tablets, yeast tablets (food mother’s life) and so on. These drugs contain mainly protease, amylase, lipase. Vaccines are inactivated when exposed to high temperatures and do not serve to immunize the organism and prevent infectious diseases. Active bacteria do not tolerate high temperatures, and can be killed by boiling water or served, thus losing their therapeutic effect. For example, Lactasexan contains lactic acid activated bacillus, Osteoporosis contains Bacillus licheniformis, Mommy Love contains Streptococcus faecalis and Bacillus subtilis, and Hershey’s contains Lactobacillus acidophilus and Bifidobacterium bifidum. These drugs are generally preferred to use less than 40 ℃ of warm water or cool water to flush, delivery. 2, easy to be oxidized and reduced by heat, such as vitamin C, vitamin B1, vitamin B2, etc., because of its nature is not stable, easy to be oxidized and reduced by heat decomposition and loss of efficacy. 3, capsule The main component of the capsule shell is gelatin, in hot water the capsule shell will rapidly dissolve and dissolve, the drug inside the rapid release, not only affect the taste, but also affect the effectiveness and safety of drugs. For example, when taking enteric capsules, hot water so that the capsule to reach the intestinal tract before the dissolution of the drug inside the role of gastric acid can not reach the intestinal tract to play the proper therapeutic effect, and the rapid release of drugs may also be on the throat, esophagus and so on the formation of irritation. Thus, the capsule should be served with warm water. 4, syrup drugs such as cough syrup, hot water will dilute the syrup, reduce the viscosity, so that it can not be covered in the inflammation of the throat and other parts of the formation of a protective film, reduce the inflammatory response of the mucous membrane, blocking the stimulus to alleviate cough. Therefore, when taking these drugs, the water temperature should be lower than 37 ℃, and should not drink more water. 5, containing volatile active ingredients of proprietary Chinese medicines Jinyinhua, Chaihu, Jingwu, Huo Xiang, mint and many other traditional Chinese medicines have a special aromatic odor, this aromatic odor is that they contain the medicinal value of the volatile oils, and volatile oils are unstable, easy to volatilize and decompose when exposed to heat. A lot of Chinese medicine granules and punch containing these Chinese medicine ingredients, it is recommended that the water temperature does not exceed 40 ℃ when brewing. 6, amoxicillin Amoxicillin is easy to hydrolyze, with the temperature increase in the rate of hydrolysis accelerated, the formation of polymers after hydrolysis can cause allergic symptoms similar to penicillin. Amoxicillin granules should be controlled when the water temperature, preferably below 40 ℃ or with cool water, should be taken immediately after rinsing, should not be left for a long time.