49 years old a year without menstruation suddenly came may be a normal phenomenon, belonging to the symptoms of perimenopausal syndrome, may also be due to endocrine disorders, polycystic ovary syndrome and other factors, and may be caused by endometrial pathology. 1. Perimenopausal syndrome: this symptom is a normal physiological symptom of a woman’s body development to a certain period of time, usually occurring at the age of 45 to 55 years old, due to the decline of ovarian function, hormone levels are unstable, the menstrual cycle is abnormal, and may appear at the age of 49 years old a year did not come to the menstruation of the situation suddenly came. 2. Endocrine disorders: The stable level of hormones in the body is broken, and women may have irregular menstruation and prolonged menstrual cycle up to one year. 3. Polycystic Ovary Syndrome: the disease may be due to genetic, environmental and other factors, 49-year-old women suffering from the disease may have abnormal menstruation, menopause for more than a year. 4. endometrial lesions: 49-year-old a year without menstruation suddenly came, may be caused by endometrial lesions, such as endometrial polyps, endometrial cancer and so on. If you are 49 years old and haven’t had your period for a year, you can go to the hospital for timely treatment and find out the cause of the problem.