After taking misoprostol, the reaction usually starts around two hours and the patient will experience significant abdominal pain, vaginal bleeding, and tissue expulsion. Misoprostol is a medical abortion medication used in conjunction with mifepristone, which helps to kill the embryonic tissue, while misoprostol is classified as a medication that promotes uterine contractions. Two days after taking mifepristone, oral misoprostol is needed to make the uterus contract and cervix dilate, which facilitates the expulsion of embryonic tissue. Misoprostol usually reacts in two hours after oral intake, and the patient will experience severe uterine contractions accompanied by obvious abdominal pain and vaginal bleeding, after which the meconium tissue and embryonic tissue will be expelled from the body with the vagina. However, a few women still cannot expel the embryonic tissue after taking misoprostol due to various factors. To sum up, it is recommended to strictly follow the doctor’s instructions to use the medicine, and if there is no discharge of embryonic tissues after using the medicine, further purging surgery is also needed.