The pathogenesis of edema with oozing out of the entire penile foreskin has a variety of factors, mainly related to infectious factors (such as gonorrhea diphtheria, staphylococcus aureus infections), allergic factors, physical factors, medical factors and so on. 1. Infectious factors: including various bacterial (such as gonorrhea diplococcus, staphylococcus aureus, etc.), fungal (such as candida albicans) caused by foreskin infection. In addition, filariasis can also appear in the early stage of the foreskin edema and exudate. 2. Allergic factors: such as insect bites, contact with lubricants, wearing condoms, penile area of the external use of drugs and angioedema, etc., can lead to local allergic reactions, causing foreskin edema oozing. 3. Physical factors: such as simple circumcision, phimosis, trauma, sex, frequent masturbation, etc., can cause edema oozing out of the foreskin. 4. medical factors: such as various ways of circumcision, circumcision neo-biectomy, penile condom repair, laser surgery, etc., will cause different degrees of postoperative edema oozing from the foreskin. The entire penile foreskin edema with oozing out, should promptly seek medical attention, under the guidance of the doctor standardized treatment, so as not to delay the condition.