Stabbing pain in the middle of the chest, consider the possibility of myocardial ischemia. There are many causes of myocardial ischemia, including lower blood pressure, reduced aortic blood supply, coronary artery blockage that can directly lead to reduced blood supply to the heart, heart valve disease, changes in blood viscosity, and lesions of the myocardium itself that can also reduce myocardial blood supply, the most common cause of which is coronary atherosclerosis. Next, there are various lesions such as inflammation, spasm, connective tissue disease, trauma, and congenital malformations. The main manifestation is chest pain with constriction-like pain when exertion and mental stress occur, radiating to the left shoulder and left upper arm of the left line, lasting 3-5 minutes and relieved after rest, often accompanied by profuse sweating. Chest tightness, palpitations, shortness of breath with strenuous activity, chest pain, chest tightness, sudden bradycardia, decreased blood pressure, syncope after a full meal, cold, or alcohol consumption. Tests are usually coronary heart disease-related. ECG is the most commonly used non-invasive test, exercise stress test, and coronary angiography can also be done.