Physiological differences have led to the fact that women’s reproductive health has always been a major factor affecting women’s health. PCOS has a high clinical prevalence and is a chronic condition that requires long-term management and therefore requires attention from women. The prevalence of polycystic ovary syndrome (PCOS) is as high as 5-10%. The main effects of the disease include: menstrual and reproductive function and glucose and lipid metabolism. It is chronic and affects the health of women almost throughout their lives. It is not curable but can be managed. Health hazards of polycystic ovary syndrome 1, recent hazards: including menstrual disorders, infertility, acne, hirsutism, obesity, etc.; most people’s understanding of the disease stays in the near-term hazards, and they think that adjusting menstruation and curing infertility is the ultimate goal, then you are wrong! 2, obstetric hazards: miscarriage rate increased by 2 times, gestational diabetes and gestational hypertension incidence increased by 3 to 4 times. One of my studies found that the prevalence of gestational diabetes in patients with PCOS fertilization assistance is about 40%, it’s really not to scare you! 3, long-term harm: including increased incidence of endometrial cancer, diabetes, metabolic syndrome, cardiovascular disease, these are lurking in the body of PCOS patients invisible killers, come very stealthy, the consequences are very serious! Without realizing it you are tripping the gun! The Need for Long-Term Management Because of its profound impact on women’s health, the disease requires long-term management. The immediate goals of long-term management are to regulate the menstrual cycle, treat hirsutism and acne, control body weight, and assist in fertility; the long-term goals are to protect the uterine lining to prevent endometrial cancer, and to prevent diabetes and cardiovascular diseases. Misconceptions in the diagnosis and treatment of polycystic ovary syndrome Misconceptions 1: Only test sex hormones, not to understand the changes in metabolic indicators; Misconceptions 2: Only regulate menstruation, once diagnosed is Dayin 35 treatment; Misconceptions 3: As long as the infertility is caused by PCOS, ovulation is promoted as soon as the diagnosis is made, regardless of the existence of metabolic abnormality, no matter how high the level of androgens are and no matter how great the impact on the obstetric complications; Misconceptions 4: Ignoring the long-term health effects of the disease; Myth 5: Arbitrary treatment regimen and lack of regular testing. Long-term management of polycystic ovary syndrome (PCOS) Long-term management of PCOS includes regular testing, development of a reasonable treatment plan, and timely adjustment of the treatment plan according to the situation, and long-term management needs to last a lifetime. (1) Regular testing (1) What to test: the test indicators include hormones (FSH, LH, PRL, T, E2, SHBG, etc.), glucose metabolism (OGTT, INS release test), lipid metabolism, and changes in liver and kidney functions, etc.; (2) When to test: pre-treatment testing is to formulate an individualized treatment plan; testing is performed once every 3-6 months during the course of treatment to understand the effect of treatment; pre-pregnancy testing is to determine whether there is any obstetrical risk and whether there is a need to test. (2) When to test: pre-treatment test is for the purpose of formulating individualized treatment plan; test once every 3-6 months during the course of treatment to know the effect of treatment; pre-pregnancy test to determine whether there are obstetric risks and whether pre-pregnancy treatment is needed. 2.Developing individualized treatment plan: Due to the high heterogeneity of PCOS patients, each patient has different performance, and individualized treatment should be carried out according to each person’s situation and requirements; 3.Lifestyle adjustment: Including exercise, dietary adjustments, stress reduction, and regular life, etc., which can help to restore ovulation and menstruation, and can prevent cancer, metabolic disorders, and other long-term complications; 4.Lowering of androgens: The first choice is oral contraceptive pill (OC), and spironolactone (SP). (OC), as well as spironolactone, dexamethasone, etc.; 5, progesterone: used for those with less severe symptoms of hyperandrogenism, and regular retreats to protect the endothelium from cancer; 6, treatment of insulin resistance: metformin is preferred; 7, infertile patients: ovulation promotion to help fertilization is adapted to patients with pregnancy requirements. Timely adjustment of the treatment program: PCOS patient treatment must consider different age stages, different requirements, different disease stages and other issues for the adjustment of the treatment program. 1, adolescent patients should pay attention to their specific stage of physiological androgens, unless androgens are particularly high do not recommend excessive intervention; 2, no fertility requirements of the treatment process regular testing of the efficacy of the treatment to determine whether to stop the drug, continue the treatment, or to adjust the program; 3, fertility requirements of the control of hormonal and metabolic disorders and as soon as possible after the ovulation to help conceive; 4, women of childbearing age to complete the birth plan still need regular testing and treatment; 5, postmenopausal women still need to pay attention to the occurrence of metabolic diseases. Post-menopausal women still need to be aware of the risk of metabolic diseases, regular testing and timely treatment. Although PCOS is complex, variable and has lifelong implications, you should never be afraid. Or the saying: “Who can not have one or two chronic diseases, from small rhinitis, hemorrhoids, to high blood pressure, heart disease, diabetes, that can be completely cured? So, be optimistic about positive control!”