Lung nodule 16mm, early stage of lung cancer is not excluded, but it can also be caused by inflammation and other factors. Lung cancer is a malignant tumor of the respiratory system caused by various factors such as smoking and heredity. When the nodule shows the characteristics of burr sign and rapid increase in size in a short period of time, the degree of malignancy is high. At this time, when the size of the nodule is 16 millimeters, if it does not involve the main bronchus at the same time, i.e., it is confined to the lungs and the visceral pleura; there are no lymph nodes and distant metastases, then it belongs to stage I, i.e., the early stage. In addition, it can also be middle or late stage. However, it can also be a nodule caused by non-cancer factors, such as inflammatory factors like pneumonia and tuberculosis. Patients should also follow the doctor’s instructions and have regular checkups or biopsies to confirm the diagnosis to avoid delaying the disease.