The ability to heal from high risk HPV16 positivity can only be determined by the results of cervical biopsy including cervical conization results. If the HPV16 positive biopsy is followed by chronic inflammation or low grade intraepithelial neoplasia, it is a benign lesion and can be treated well. It is recommended to use the medication povidone suppository or interferon every night for 7-10 days continuously, 1 month for a course of treatment, that is, 3 months of time need 3 courses of treatment. It is also necessary to increase your own exercise, such as jumping rope and running, to increase your own immunity, which can help turn HPV negative. 3 months or six months later to recheck HPV, generally can be treated well. If the cervical biopsy results suggest a high-risk lesion, this is the time to undergo a cervical conization procedure. When cervical conization suggests cancer, there is no cure for this condition because there is no cure for cancer, but early surgical treatment is performed to remove the causative agent. For example, laparoscopic extensive total uterus plus bilateral adnexa plus pelvic lymph node dissection can be performed, and postoperative chemotherapy and radiation therapy can be administered to extend life.