Breastfeeding is possible after the use of topical anesthetics and generally requires an interval of at least 24 hours before breastfeeding. In most cases, the use of local anesthetic during breastfeeding is not recommended to avoid affecting the quality of breast milk, which in turn may have adverse effects on the development and health of the baby. If necessary due to the treatment of the condition, a safer drug should be carefully selected after examination and comprehensive judgment by a physician. Treatment with local anesthetics should be followed by a breastfeeding interval of at least 24 hours, because the drug may pass through breast milk and enter the baby’s body during breastfeeding, which may have an impact on the baby’s growth and development. If the anesthetic enters the breast milk, it may cause gastrointestinal reactions in the infant, such as nausea, vomiting, or even apnea, and even central nervous system and cardiotoxic reactions in particularly sensitive cases, leading to a poor prognosis for the infant. During the breastfeeding period, dietary treatment is mostly used to improve the mother’s discomfort and minimize the impact on the infant, and the appropriate medication is chosen after the infant is weaned. In addition, a light and nutritious diet and adequate rest should be taken care of during the treatment period to promote recovery.