A male chromosome translocation is an abnormality in the position of a gene segment on the chromosome of a male patient. The number and position of normal chromosomes in the human body are normal and fixed. In chromosome translocation, a segment of the chromosome is broken and exchanged in the process of rejoining, which is called chromosome translocation. Men with chromosomal translocations usually have a normal phenotype, which means that they do not have any of the disorders caused by the translocation. Men with chromosomal translocations are less likely to produce normal gametes, which can lead to miscarriages and fetal defects. However, it is still possible to produce normal gametes, so natural conception may result in a normal baby. In case of recurrent embryonic arrest, three generations of IVF are done if necessary. Patients who have checked that they are patients with chromosomal translocations should prepare for pregnancy scientifically under the guidance of their doctors.