Case: Since 15 years old after puberty development, Xiao Li’s breasts have been “crazy growth”, much larger than girls of the same age, wearing D cups in junior high school, and now is a G cup. After reaching childbearing age as an adult, Li has not been pregnant, menstrual disorders, to the hospital for examination, only to find that the local growth of fat breasts, infertility is “obese polycystic ovary syndrome” caused by the trouble. It seems that being too “outstanding” may not be a good thing sometimes. So, what is this polycystic ovary syndrome all about? The face of polycystic ovary syndrome may seem a bit rusty and less familiar than ovarian cancer, breast cancer, cervical cancer and other diseases. However, in clinical practice, polycystic ovary syndrome has a very high prevalence and is commonly seen in adolescence and reproductive age, and is an endocrine disorder syndrome. The cause of the disease is not yet clear, but is generally thought to be related to hypothalamic-pituitary-ovarian axis malfunction, adrenal gland dysfunction, genetics, metabolism and other factors. What are the symptoms of polycystic ovary syndrome? Polycystic ovary syndrome is usually easily overlooked and most patients are only diagnosed when they visit an infertility clinic. The following are some of the major symptoms that women should be aware of: Irregular menstruation The typical symptoms of polycystic ovary syndrome are irregular menstruation starting from menarche, including sporadic menstruation and amenorrhea. Due to the instability of menstruation during adolescence and the lack of knowledge about physiological health, girls are not aware of the need to seek medical attention, which can easily delay the disease. In middle-aged and young adults, the condition develops into secondary amenorrhea and amenorrhea. Endocrine disorders Endocrine disorders are mainly characterized by excessive secretion of androgens in the body, which can lead to masculinity and hirsutism. For example, the hair on the lips, chest, beard, anus, arms and calves becomes more dense and thicker. Typically, the patient may develop acanthosis nigricans, which is a symmetrical appearance of gray-brown pigmentation on the skin of the back of the neck, axillae and groin. Obesity Polycystic ovary syndrome can also cause unexplained fatness and result in large breasts, bucket waist and buttocks, a typical case is Xiao Li mentioned at the beginning of the article. The relationship between obesity and polycystic ovary syndrome is complex, and may be related to a decrease in insulin sensitivity or an increase in androgens. Infertility is caused by menstrual disorders, immature follicles or anovulation due to hormonal disorders or lack of basic ovarian function, which often leads to egg failure, or abnormal growth of the endometrium due to hormonal reasons, which makes it difficult for fertilized eggs to implant and develop, resulting in infertility. Bilateral ovarian enlargement is also difficult to confirm by palpation, and is often detected by ultrasound, which reveals that the ovaries are twice as large as normal and hard. It is important to recognize the symptoms of polycystic ovary syndrome, especially in adolescent girls, and to pay attention to changes in their bodies, such as sudden increases in hair and weight for no apparent reason. In addition, women should relax, although the cause of this endocrine disorder syndrome has not been clearly identified, stress and depression may also trigger or aggravate the condition, so women should take good care of their daily health.