A hard lump in the middle of a woman’s stomach and stomach pain may be intestinal tuberculosis, ectopic pregnancy, appendicitis, etc., need to improve the abdominal ultrasound and other auxiliary examinations, choose cephalosporin and other antibiotics or surgical treatment. The hard lump in the middle of the stomach and the accompanying stomach pain can be caused by many situations, both may be intestinal tuberculosis, appendicitis around the abscess and other digestive diseases, but also may be a ruptured ectopic pregnancy, endometriosis and other obstetrics and gynecology diseases. First of all, we should consult a doctor in time to improve the abdominal ultrasound, abdominal examination and other auxiliary examinations to clarify the cause of the disease, and then choose the treatment mode according to the cause of the disease. The abdominal pain caused by intestinal tuberculosis lumps need isoniazid, rifampicin and other anti-tuberculosis drugs, because it has a certain degree of ear and kidney toxicity need to be used under the guidance of a doctor; and ectopic pregnancy rupture of the abdominal pain caused by hard lumps need emergency surgical treatment, the rupture of the gestational sac leading to hemorrhage and even life-threatening. It is recommended that sudden or continuous progress of abdominal pain should be timely medical care, detailed description of the relevant medical history to improve the abdominal ultrasound and other ancillary examinations to clarify the cause of the disease, and then take the corresponding medication or surgical treatment in a timely manner.