The second recurrence of brain tumor will mainly manifest nausea and vomiting, epileptic convulsions, increased intracranial pressure and neurological deficits and other symptoms. 1. Nausea and vomiting: when the brain tumor recurs, it can lead to the stimulation of vagus nerve center, which will make the patient suffer from frequent nausea and vomiting. 2. Epileptic convulsions: the compression of local nerves in the brain by the brain tumor may cause generalized epileptic convulsions and speech dysfunction, and in serious cases, it may also lead to coma of the patient. 3. Increased intracranial pressure: the recurrence of brain tumor will cause increased intracranial pressure, which usually manifests as headache, dizziness, and will lead to poor venous blood return of retina, resulting in optic nerve papillae edema, and the symptoms of obvious vision loss or even blindness. 4. Loss of nerve function: when brain tumor recurs, it will also cause loss of hearing, vision, facial sensation, limb movement and limb sensation and other nerve functions. Once the above symptoms or other uncomfortable symptoms appear, it is necessary to pay great attention to them, go to the hospital for examination in time to determine whether there is the situation of brain tumor recurrence, and carry out targeted treatment under the guidance of professional doctors in combination with individual situation to maximally improve the quality of patients’ survival.