Hiccups with burning sensation in the chest may be related to gastroesophageal diseases, increased abdominal pressure, diaphragm stimulation or diaphragmatic hernia, heart disease, etc., which need to be combined with other symptoms and related examinations to clarify the cause. 1. Gastroesophageal diseases: reflux esophagitis, chronic gastritis, etc. can cause excessive secretion of gastric acid, which is manifested as burning sensation in the chest and hiccups. 2. Increased abdominal pressure: abdominal tumors, abdominal diseases, obesity, overeating, gastric dilatation, gastrointestinal flatulence, etc. can cause increased abdominal pressure, induced by hiccups, hiccups in the case of intense, will make part of the stomach content reflux, causing burning sensation in the chest. 3. Diaphragm stimulation or diaphragmatic hernia: when there is subphrenic abscess, pneumonia combined with septal pleurisy, diaphragmatic hernia, etc., so that the diaphragm is stimulated, which is easy to cause hiccups and accompanied by burning sensation in the chest. At this time, hiccups last longer. 4. Heart disease: when heart enlargement, arrhythmia, angina pectoris and other diseases stimulate the diaphragm, it can also cause hiccups with burning sensation in the chest, and it is recommended to go to cardiovascular medicine department for differentiation. When the above symptoms occur, please consult a doctor in time, under the guidance of a professional physician to clarify the cause of the disease, and follow the doctor’s instructions for treatment.