The incidence of glossopharyngeal neuralgia is very low and it is a rare disease. The disease is most common in people around 50 years of age and is characterized by paroxysmal, severe, knife-like pain in one side of the pharynx (lateral pharyngeal wall, tonsils), soft palate, root of the tongue, behind the ear and deep part of the ear canal, induced by actions such as eating, brushing teeth and speaking. At present, conservative treatment (e.g., taking carbamazepine, phenytoin sodium, etc.) is ineffective in the treatment of linguopharyngeal neuralgia, which is a paroxysmal, severe pain occurring in the distribution area of the linguopharyngeal nerve. The etiology is unknown and may be due to demyelination of the nerve, which causes impaired nerve afferent impulses. Among the secondary causes, it includes vascular abnormalities and tumors in the pontocerebellum and cerebellar horn, pearl retinitis, vertebral artery disease, and extracranial tumors occurring in the carotid artery, pharynx, larynx, and tonsils. It is thought that extracranial vascular disorders, such as internal carotid artery occlusion and external carotid artery stenosis, may also be the cause of this disease. Symptoms and signs of glossopharyngeal neuralgia 1. Prevalent age: 35-50 years old. 2. Site of onset: tonsillar region, pharynx, tongue root, neck, deep ear canal, and posterior mandibular region. 3. Nature of pain: paroxysmal severe pain, such as knife-like, stabbing-like, painful convulsions. 4.Time of pain: frequent in the morning and morning, and there may be episodes during sleep, this point can be distinguished from trigeminal neuralgia. 5.Sense of foreign body and infarction: there is a sense of foreign body and infarction in the pharynx and larynx at the onset, which leads to frequent coughing. 6. Pain-triggering factors: Pain can be triggered by palpation, also known as “trigger point”. It is commonly found in the tonsil area, external auditory canal and tongue root. Pain can be triggered whenever swallowing, chewing, yawning or coughing. 7. There are intermittent periods. 8. The patient has dehydration and wasting. It is caused by the fear of pain and less food intake. 9.Severe cases may have arrhythmia, cardiac arrest, fainting, convulsions, seizures, laryngeal spasms, and excessive secretion of parotid glands.