The most serious degree of otitis media is that the inflammation spreads and involves the patient’s skull leading to intracranial infection, and the patient may suffer from high fever, convulsions, and even life-threatening conditions. Therefore, patients with otitis media must pay attention to actively control the patient’s inflammation. Otitis media is mainly manifested as ear pus pain, stuffy feeling, tinnitus, hearing loss, if the patient is not actively to control or repeated episodes of inflammation, it is easy to lead to the middle ear cavity inside the formation of granulation, and even destruction of bone, before involving the patient’s intracranial leading to serious infections. After the patient actively apply antibiotics, such as cefuroxime sodium injection or amoxicillin injection, and actively control the inflammation, the patient’s inflammation will not appear to spread.