Hepatology IV is not a test for hepatitis B. The four liver function tests mainly include glutamic aminotransferase, glutamic oxalacetic aminotransferase, total bilirubin and direct bilirubin, etc. The four liver function tests set by different hospitals may differ slightly. The hepatitis B test is mainly determined by the hepatitis B five items and the hepatitis B virus DNA quantification. The hepatitis B five items are the initial screening items for hepatitis B, while the hepatitis B virus DNA quantification is a more accurate test. The five tests for hepatitis B mainly include hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody and hepatitis B core antibody. It should also be noted that a patient with normal liver function does not mean that hepatitis B does not exist, and a patient with hepatitis B does not necessarily cause abnormal liver function, so very often liver function and hepatitis B tests are combined, which is more conducive to clinical judgment and guidance of clinical treatment. Patients with hepatitis B major tri-positive, if there is a significant increase in transaminases, it is likely the best time for antiviral therapy, but it needs to be combined with hepatitis B virus DNA quantification to further determine.