The N-terminal brain natriuretic peptide precursor is usually referred to as NT-proBNP, and elevation is commonly seen in patients with heart failure, but also in tachycardia and renal insufficiency. BNP refers to brain natriuretic peptide, which is mainly secreted by ventricular myocytes and has a negative feedback effect on ventricular filling pressures in response to changes in ventricular wall tension. NT-proBNP is a BNP iso-molecular-weight-producing substance, and it is an important indicator for the diagnosis and prognosis of heart failure. Elevated NT-proBNP is common in patients with heart failure, and if NT-proBNP levels are still high in those who have already received treatment, it suggests a poor prognosis. In addition, elevated NT-proBNP can be seen in conditions such as left ventricular hypertrophy, tachycardia, myocardial ischemia, pulmonary embolism, hypoxia such as chronic obstructive pulmonary disease (COPD), renal insufficiency, and cirrhosis of the liver. Therefore, it is recommended to go to the hospital for a clear diagnosis if NT-proBNP is found to be elevated on examination.