Chronic gonorrhea in men is usually treated with antibiotics, with an average treatment period of mostly about 10-14 days and a healing time of usually 2 weeks, but with recurrence. Chronic gonorrhea is usually a condition that occurs when the infection spreads due to the lack of timely treatment or inadequate treatment. The treatment is intramuscular injection of daikonomycin or ceftriaxone for more than 10 consecutive days, combined with oral metronidazole or doxycycline, and if all clinical symptoms disappear after 2 weeks and the urethral discharge is taken and the culture of gonococcus is negative, it can be considered clinically cured. If, during the course of treatment, the Neisseria gonorrhoeae that causes the patient’s disease develops drug resistance, a drug sensitivity test should be performed in a timely manner and the appropriate antibiotic should be selected according to the results to avoid delaying the disease. Young men and women should pay attention to cleanliness, minimize unclean sexual intercourse, and take effective protective measures such as wearing condoms during sexual intercourse, which can effectively reduce the occurrence of gonorrhea.