The HPV vaccine is above 95% safe and is mainly used for the prevention of cervical cancer, the vaccine appeared late. The cervical cancer vaccine is like other vaccines, such as the measles vaccine, the diphtheria vaccine, and the rabies vaccine. Most individuals will have an effective protective effect after the injection, only a very small percentage will have some unsafe effect, mainly related to the individual’s constitution or if the woman has an infection, fever, allergy, etc. before the injection. The vaccination will stimulate the body to produce a certain immune response, so it may lead to fever, redness, swelling and erythema. This condition will subside after 12 days of symptomatic treatment and will not pose a threat to life and health. Any vaccination carries certain risks and therefore cannot be 100% safe and effective and needs to be treated correctly.