1.Why is bladder cancer the most prevalent tumor among urological tumors?
Bladder cancer is the most common malignant tumor in the urinary system, which may be related to the following factors: urine produced by the kidneys is discharged to the bladder through the ureter and stays in the bladder for the longest time; combined with lower urinary tract obstruction, easy to combine with chronic bladder infection and stone stimulation, which leads to high incidence of bladder tumors in the urinary system.
2.What can cause bladder cancer? What chemicals can cause bladder cancer?
The occurrence of bladder cancer is a complex, multifactorial and multi-step pathological process, and the causes of its development are not fully understood. Occupational exposure was the first known risk factor for bladder cancer, and about 20% of bladder cancers are caused by occupational factors, including those involved in textiles, dye manufacturing, rubber chemistry, pharmaceutical and pesticide production, paint, leather, and aluminum, iron, and steel production. Diesel exhaust accumulation can also increase the risk of bladder cancer. Other possible causative factors include chronic infections (bacterial, schistosomal and HPV infections, etc.), application of the chemotherapeutic drug cyclophosphamide (incubation period 6-13 years), abuse of painkillers containing finasteride (more than 10 years), recent and long-term history of pelvic radiotherapy, long-term consumption of water with high arsenic content and chlorine disinfected water, coffee, artificial sweeteners and hair dye.
3.Does smoking and alcohol abuse cause bladder cancer?
Smoking is the most certain risk factor for bladder cancer, about 30%-50% of bladder cancers are caused by smoking, smoking can increase the risk rate of bladder cancer by 2-4 times, and the risk rate is proportional to the intensity and duration of smoking.
There has been no definite conclusion about the relationship between alcohol intake and the occurrence of bladder cancer in the medical field. It is currently believed that moderate alcohol consumption is not significantly associated with the occurrence of bladder cancer, but long-term alcohol abuse may increase the incidence of tumors by affecting the systemic immune status.