The best way to handle a 39-degree fever is with medication, fluid replacement, and physical cooling. Drugs such as ibuprofen and acetaminophen are often used to help the temperature drop. At the same time, the patient needs to go to the hospital in time to complete the relevant examination, to clarify the cause of fever, and to treat the cause. If you need to use drugs, you need to use under the guidance of a doctor. 1. Medication: Patients with fever up to 39 degrees are prone to convulsions and seizures caused by high fever. It is necessary to lower the temperature in time, can be oral ibuprofen, acetaminophen and other drugs to lower the temperature. 2. Fluid replenishment: During the period of fever, patients consume more energy and need to replenish enough water, nutrition and food. Drink plenty of water and give enough sugar and vitamin supply. Patients who are unable to eat on their own can be given glucose intravenously to replenish energy. 3. Physical hypothermia: For those with high body temperature of 39 degrees, warm water can be used to cool down the body, wearing an ice cap on the head, ice packs on the aorta passing through the place and other physical methods. The cause of fever is unknown, usually do not advocate a rush fever, so as not to cover up the condition, should focus on finding the cause of the disease as soon as possible. Those with high body temperature can take cooling measures. It is recommended that the patient go to the hospital in a timely manner to clarify the cause of the disease.