Acne on the cheeks is medically referred to as acne. Acne on the cheeks that doesn’t go away can be caused by factors such as lack of formal treatment, formation of cysts, and secondary to other infections. 1. Unregulated treatment: Acne is mostly caused by Propionibacterium acnes infection, exuberant sebaceous gland secretion, abnormal keratinization of cells around hair follicles, etc. If the cause is not eliminated by unregulated treatment, acne on the cheeks will not go away. 2. Formation of cysts: Some cystic acne is more difficult to treat and the treatment period is longer, so it is difficult to eliminate acne in a short period of time, resulting in acne on the cheeks that never goes away. 3. Secondary other infections: When acne grows on the cheeks, if the skin breaks down due to improper treatment, it is easy to secondary other infections, inducing folliculitis, boils and other diseases, which will also cause acne not to go away. There are many reasons why acne on the cheeks does not go away, and it is recommended to avoid the triggers to avoid recurring episodes.